One of the (great) challenges that you may have with your WordPress blog (or site) is how it scales with a lot of traffic. This talk is presented by Ryan Allen the architect of the Envato network (which is huge) so it would be good to give it a listen.
Matthew Snider says
Great video, I have watched it previously. With a solid server, caching implemented and the correctly written code schema, you should be solid. I have a buddy who is running 2.7 still and gets over 50k a day. Small potatoes compared to Envato but site is running fine on WP.