Often times when I sit down to design something I have an image (or two) in mind already. In fact, I typically have some great graphic imagery but I don’t have, conceptually, an idea of how to build out the colors of the rest of the site.
So, I’ll let the image lead the way.
One tool that I’ve used is the uber-cool Color Palette Generator.
I can take any image, upload it quickly, and it spits back a CSS file that matches the colors of the image or as a color swatch for Photoshop.
See my lovely mug here with the camera? I’ve got the color palette to choose from (if I were making a site using this image).

Awesomeness. Check it out for yourself!

nice one, but that is a tool that is going into the must use for 'new blog with WP 2.7/8 hosted on lusion dot co dot za in cahootz with friend Ron'
with in a month
it is time
So many great uses from this one! Thanks!
Sure thing!
Some of these apps are definitely great. Be sure to check out kuler.adobe.com online, I use that quite a bit. Many different palettes, and you can also create your own and save them. Both an online version and a local app available.
Gabe, right on. thanks for adding that!
Unrelated but didn't see an email address. Thought this might be something that interests you
http://www.avc.com/a_vc/2009/02/introducing-blogr…
word!
sweet tool. actually have a friend that is looking for a tool like this. thanks for sharing.